Fairbrother KJ, Heasman PA: Anticalculus agents. J Clin Periodontol ; the research associated with the development of anticalculus agents and to evalu-. Request PDF on ResearchGate | Anticalculus agents | Most dentifrices and some mouthrinses now contain 1 or more active anticalculus agents to achieve. With the help of antiplaque and anticalculus agents. Chemical plaque control – Rationale. Gingivitis & periodontitis are highly prevalent diseases and.

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Surfactants suitable for this purpose include polysorbates and poloxamers. The composition of Claim 1 in the form of a dentifrice wherein the pharmaceutically acceptable topical oral carrier comprises a dental abrasive.

Water employed in the preparation of the commercially suitable compositions should preferably be of low ion content and free of organic impurities. SUMMARY [] In a first aspect, the present invention provides an oral care composition for treating or preventing calculus, which composition comprises an anticalculus agent and an antibacterial agent comprising a biphenol compound obtainable from Magnolia officinalis, wherein the composition is free of phosphate-containing anticalculus agents.

Anti-calculus tests use a similar model of in vitro plaque growth which also involves periodic exposure antlcalculus crystal growth inhibitors and plaque mineralising solution. In other embodiments, the antibacterial ingredient comprises an extract of magnolia. Preparation of zinc citrate and of zinc citrate-containing oral care compositions. During this week, the person does not brush her teeth.

The oral care composition according to any preceding claim, wherein the composition comprises at least 1.

EP EPB1 en This water-soluble fluoride aggents is typically present in the compositions of this invention in an amount sufficient to give a fluoride concentration of from about 0. Sodium lauryl sulfates, sodium lauroyl sarcosinate and sodium coconut monoglyceride sulfonates are examples of anionic surfactants of this type.

The zinc salt is found to improve the delivery of the biphenol compound. In common with other carrier components, in certain embodiments, the surfactant should be phosphate-free. Suitable binders include, but are not limited to, natural gums such as gum karaya, gum arabic, and gum tragacanth; polysaccharide gums such as xanthan gum; and other natural products such as carrageenan; chemically modified natural products such as those based on cellulose esters, that is, carboxylmethylcellulose CMChydroxyethylcellulose HECand hydroxypropylcellulose HPC ; and synthetic binders such as polyvinylpyrrolidone; and water soluble salts of cellulose ethers such as sodium carboxymethyl cellulose and sodium carboxymethyl hydroxyethyl cellulose.


Other optional ingredients include synthetic or natural anionic polymeric polycarboxylates, polysaccharides, and polysulfates. If not prevented or removed, plaque may become embedded with mineral salts, containing calcium and phosphate, to form a hard crusty deposit, calculus or tartar, on the teeth.

Anticalculus agents for the treatment, control, and prevention of periodontal disease.

Anti-plaque and Anti-calculus Oral Care Product Testing Anti-plaque and anti-calculus laboratory testing for oral care products to evaluate anti-bacterial, anti-adhesion or enzyme inhibition agents or crystal growth inhibition agents In vitro anti-plaque and anti-calculus testing of oral care products can help to assess product performance.

In certain embodiments of the present invention, the antibacterial ingredient in the active composition comprises one or more active compounds that have been isolated from an extract of magnolia.

Inspection Validating the specifications, value and safety of your raw materials, products and assets. However, users may print, download, or email articles for individual use. Oral composition exhibiting improved uptake and retention of antibacterial compounds on dental tissue surfaces.

Instructions setting out such a schedule may be provided in commercial packaging with the product.

Anticalculus agents for the treatment, control, and prevention of periodontal disease.

For example, while dentifrice containing no zinc salt Formulas 9 provided the delivery of Also preferred is a zincxitrate: The composition of Claim 1 in the form of a solution selected from a mouthwash, a mouth rinse, a dental solution, and a mouth spray, wherein the anticslculus carrier comprises a material selected from a humectant, ethanol, and a nonionic surfactant. Nutrients can also be present in the oral composition of this invention, on condition that they are compatible with the Agenys.

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Country of ref document: The following non-limiting examples further antivalculus and demonstrate preferred embodiments within the scope of this invention. The amounts listed are weight percentages of the compositions. The dentifrice and water mixture is stirred continuously for at least 30 minutes to ensure the mixture is homogenous.


Evaluating how your products and services meet and exceed quality, safety, sustainability and performance standards. BR Ref legal event code: One suggested mechanism by which many anticalculus agents inhibit calculus formation involves an increase of the activation energy barrier thus inhibiting the transformation of precursor amorphous calcium phosphate to HAP, Studies have shown that there agentx a good correlation between the ability of agebts compound to prevent HAP crystalline growth in vitro and its ability to prevent calcification in vivo, provided that the compound is stable in and inert to other components in an oral care composition and to saliva in the oral cavity.

However, remote access to EBSCO’s databases from non-subscribing institutions is not allowed if the purpose of the use is for commercial gain through cost reduction or avoidance for a non-subscribing institution. The term “compatible” as used herein, means that the components are capable of being co-mingled with one another, in a manner such that there is no interaction which would substantially reduce the efficacy of the oral composition under ordinary use conditions.

Such compositions include mouthwashes, mouth rinses, mouth sprays, dental treatment solutions, toothpastes, liquid dentifrices and the like and are more fully described hereinafter. We are particularly adept in designing bespoke in vitro models to cater for your specific requirements. US USB2 en